7-ethyl-10-(chlorocarbonyloxy) camptothe cin

Incazelo emfushane:

I-CAS no:

Izakhiwo zamakhemikhali: I-Irinotecan Intermediates

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isebenzisa

I-7-ethyl-10-(chlorocarbonyloxy) camptothe cin isetshenziswa njengendawo emaphakathi ye-Irinotecan.
Isidakamizwa se-Irinotecan antitumor.Kuyi-inhibitor ye-DNA synthesis.Iyingxenye yokwenziwa kwe-camptothecin;Isetshenziselwa ukulungisa i-irinotecan hydrochloride ne-irinotecan hydrochloride trihydrate;Izivivinyo ezinkulu zemitholampilo zibonise ukuthi i-irinotecan hydrochloride inemiphumela esobala yokuvimbela izimila ezihlukahlukene, ezifana nomdlavuza wekoloni, umdlavuza wamaphaphu amancane, umdlavuza we-rectal kanye ne-leukemia, futhi isasebenza kahle ezimweni eziphikisana ne-fluorouracil.Ngakho-ke, i-irinotecan hydrochloride idonse ukunaka okubanzi emhlabeni wonke.

Ulayini Womkhiqizo Ohlanganisiwe Wezinsiza

Isitifiketi

I-JIN DUN Medical ineIziqu ze-ISO futhi ihlangabezana namazinga okukhiqiza e-GMP, kuqashwe ochwepheshe basekhaya nabangaphandle abanolwazi olunzulu lokuqondisa i-R&D yenkampani.

Izinzuzo Zokwenza Ngokwezifiso Kwezokwelapha

TECHNOL OGY UBUHLE
●I-High Pressure Catalytic Hydrogenation.I-High Pressure Hydrogenolysis Reaction .Ukusabela kwe-Cryogenic (<-78%C)
● I-Aromatic Heterocyclic Synthesis
●Ukusabela Kabusha
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Ukusabela kukaGiignard

I-JIN DUN R&D

Izisetshenziswa

Ilebhu yethu inezinsiza ezihlukahlukene zokuhlola nokuhlola, njenge: NMR (Bruker 400M), HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, i-Differential Scanning Calorimeter (DSC), i-Electron Microscope...

Ithimba le-R&D

I-Jindun Medical ineqembu labasebenzi abangochwepheshe be-R&D, futhi isebenzisa ochwepheshe abaningi bokwenziwa kwezidakamizwa basekhaya nabangaphandle ukuze baqondise i-R&D, okwenza ukuhlanganiswa kwethu kunembe kakhudlwana futhi kusebenze kahle.

Ukwabelana Kwamacala

Sisize izinkampani ezimbalwa eziphezulu zasekhaya ezithaka imithi, njengeI-Hansoh, i-Hengrui ne-HEC Pharm.Lapha sizokhombisa ingxenye yazo.

Ikesi Lokwenza Ngokwezifiso:

Inombolo yeCas: 110351-94-5

Ikesi Lokwenza Ngokwezifiso:

Inombolo yeCas: 144848-24-8

Ikesi Lesithathu Lokwenza Ngokwezifiso:

Inombolo yeCas: 200636-54-0

Imodi Yokubambisana

1.Enza ngendlela oyifisayo i-New Intermediates noma ama-API.Ngokufanayo nokwabelana kwecala elingenhla, amakhasimende anezidingo ze-Intermediates ethile noma ama-API, futhi awakwazi ukuthola imikhiqizo edingekayo emakethe, lapho-ke singasiza Ukwenza Ngokwezifiso.

2.Ukuthuthukisa Inqubo Yemikhiqizo Emidala.Ithimba lethu lizosiza Ukuthuthukisa futhi lithuthukise ukukhiqiza okunjalo okuyindlela yokusabela endala, izindleko zokukhiqiza ziphezulu, nokusebenza kahle kuphansi.Singahlinzeka ngemibhalo egcwele yokudluliswa kobuchwepheshe kanye nokuthuthukiswa kwenqubo, sisize ikhasimende ngokukhiqiza okuphumelelayo.

Ukusuka kokuhlosiwe kwezidakamizwa kuye kuma-IND, i-JIN DUN Medical ikunikezaizixazululo zomuntu siqu ze-R&D zokuma okukodwa.

I-JIN DUN Medical iphikelela ekwakheni iqembu elinamaphupho, ukwenza imikhiqizo enesizotha, ecophelelayo, eqinile, futhi siphume konke ukuze sibe uzakwethu othembekile nomngane wamakhasimende!

Okwedlule: 1,4′-Bipiperidine]-1′-carbonyl chloride HCl

Olandelayo: I-7-ethyl-10-hydroxycamptothecin

Bhala umyalezo wakho lapha futhi usithumelele wona