“Ikhwalithi kuqala, Ukwethembeka njengesisekelo, Usizo oluqotho kanye nenzuzo efanayo” kuwumbono wethu, emzamweni wokwakha ngokungaguquki futhi siphishekele ubuhle Bentengo Eqhudelana Yefektri Isitolo Sezinto Eziphilayo Esimaphakathi BMK Pmk Powder 1-Propanol, 2-Methyl-2- [(phenylmethylene) Amino]- CAS 22563-90-2, Ikhwalithi ephezulu izoba yisici esibalulekile sokuthi leyo nhlangano ihluke kwezinye izimbangi.Ukubona ukuthi Uyakholwa, ufuna ulwazi olwengeziwe?Isivivinyo nje ezintweni zayo!
"Ikhwalithi yokuqala, Ukwethembeka njengesisekelo, Usizo oluqotho kanye nenzuzo efanayo" kuwumbono wethu, emzamweni wokudala ngokungaguquki futhi siphishekele ubuhleI-China Pharmaceutical Intermediates kanye ne-Agrochemical Intermediates, Ukuze uthole ulwazi olwengeziwe ngathi kanye nokubona zonke izinto ezithengiswayo, sicela uvakashele iwebhusayithi yethu.Ukuze uthole ulwazi olwengeziwe sicela ukhululeke ukusivumela ukuba sazi.Ngiyabonga kakhulu futhi ngifisela ibhizinisi lakho njalo libe lihle!
I-3′-Amino-2′-hydroxy-[1,1'-bipheny]-3-carboxylic acid isetshenziswa njengendawo emaphakathi ye-Eltrombopag.
I-Eltrombopag, eyakhiwe yi-GlaxoSmithKline (GSK) e-UK futhi kamuva yathuthukiswa ngokuhlanganyela ne-Novartis e-Switzerland, ingeyokuqala futhi iwukuphela kwe-molecule encane egunyazwe i-non-peptide TPO receptor agonist emhlabeni.I-Eltrombopag yagunyazwa yi-FDA yase-US ngo-2008 yokwelapha i-idiopathic thrombocytopenic purpura (ITP), nango-2014 ukuze kwelashwe i-aplastic anemia enzima (AA).Futhi isidakamizwa sokuqala esigunyazwe yi-US FDA sokwelapha i-AA eminyakeni engama-30 yakamuva.
Ngo-December 2012, i-US FDA yagunyaza i-Elthrombopag yokwelapha i-thrombocytopenia ezigulini ezine-hepatitis C (CHC) engapheli, ukuze iziguli ze-hepatitis C ezinokubikezelwa okungekuhle ngenxa yokubala kweplatelet ephansi zikwazi ukuqala futhi zilondoloze ukwelashwa okujwayelekile okusekelwe kwe-interferon kwezifo zesibindi.NgoFebhuwari3, 2014, i-GlaxoSmithKline yamemezela ukuthi i-FDA inikeze ukuphumelela komuthi wokwelapha i-Eltrombopag wokwelapha i-hemopenia ezigulini ezine-chemicalbook aplastic anemia (SAA) enzima kakhulu engazange iphendule ngokugcwele ku-immunotherapy.Ngomhla zingama-24 ku-Agasti, i-2015, i-US FDA igunyaze i-Eltrombopag yokwelashwa kwe-thrombocytopenia kubantu abadala kanye nezingane ezineminyaka engu-1 nangaphezulu ezine-immune immune thrombocytopenia (ITP) ezingenampendulo eyanele ku-corticosteroids, i-immunoglobulins noma i-splenectomy.NgoJanuwari4, 2018, i-Eltrombopag yagunyazwa ukuthi ifakwe ohlwini e-China ukuze zelashwe i-immune immune thrombocytopenia (ITP).
“Ikhwalithi kuqala, Ukwethembeka njengesisekelo, Usizo oluqotho kanye nenzuzo efanayo” kuwumbono wethu, emzamweni wokwakha ngokungaguquki futhi siphishekele ubuhle Bentengo Eqhudelana Yefektri Isitolo Sezinto Eziphilayo Esimaphakathi BMK Pmk Powder 1-Propanol, 2-Methyl-2- [(phenylmethylene) Amino]- CAS 22563-90-2, Ikhwalithi ephezulu izoba yisici esibalulekile sokuthi leyo nhlangano ihluke kwezinye izimbangi.Ukubona ukuthi Uyakholwa, ufuna ulwazi olwengeziwe?Isivivinyo nje ezintweni zayo!
Intengo Yokuncintisana yeI-China Pharmaceutical Intermediates kanye ne-Agrochemical Intermediates, Ukuze uthole ulwazi olwengeziwe ngathi kanye nokubona zonke izinto ezithengiswayo, sicela uvakashele iwebhusayithi yethu.Ukuze uthole ulwazi olwengeziwe sicela ukhululeke ukusivumela ukuba sazi.Ngiyabonga kakhulu futhi ngifisela ibhizinisi lakho njalo libe lihle!