I-Quality First, kanye ne-Client Supreme iyisiqondiso sethu sokuletha usizo olungcono kakhulu kubathengi bethu. Kulezi zinsuku, besizama konke okusemandleni ethu ukuba phakathi kwabathumeli bangaphandle abafanelekile ngaphakathi kwenkundla yethu ukuze sanelise abathengi okwengeziwe abazodinga isitayela sase-Europe 3′- IHydroxy-3-Biphenylcarboxylic Acid Citric Acid 77-92-9, Ngaphezu kweminyaka engu-8 yebhizinisi elincane, manje sesiqongelele ulwazi olucebile nobuchwepheshe obuthuthukile phakathi nokukhiqizwa kwemikhiqizo yethu.
I-Quality First, kanye ne-Client Supreme iyisiqondiso sethu sokuletha usizo olungcono kakhulu kubathengi bethu. Kulezi zinsuku, besizama okusemandleni ethu ukuba phakathi kwabathumeli bangaphandle abafanelekile ngaphakathi kwenkundla yethu ukuze sanelise abathengi okwengeziweI-China 77-92-9 kanye ne-CAS 77-92-9, Ngokusekelwe emugqeni wethu wokukhiqiza ozenzakalelayo, isiteshi sokuthenga izinto ezizinzile kanye nezinhlelo ezisheshayo zenkontileka engaphansi kwakhiwe ezweni laseChina ukuze kuhlangatshezwane nemfuneko ebanzi nephakeme yamakhasimende eminyakeni yamuva.Besilokhu sibheke ngabomvu ukubambisana namakhasimende engeziwe emhlabeni wonke ukuze sithuthuke ngokufanayo futhi sizuze ngokufanayo!Ukwethemba kwakho nokugunyazwa kwakho kuwumvuzo ongcono kakhulu wemizamo yethu.Ngokuhlala sithembekile, sisungula izinto ezintsha futhi sisebenza kahle, silindele ngobuqotho ukuthi singaba ozakwethu bebhizinisi ukuze sakhe ikusasa lethu eliqhakazile!
I-2′-hydroxy-3′-nitro-3-biphenylcarboxylic acid isetshenziswa njengendawo emaphakathi ye-Eltrombopag.
I-Eltrombopag, eyakhiwe yi-GlaxoSmithKline (GSK) e-UK futhi kamuva yathuthukiswa ngokuhlanganyela ne-Novartis e-Switzerland, ingeyokuqala futhi iwukuphela kwe-molecule encane egunyazwe i-non-peptide TPO receptor agonist emhlabeni.I-Eltrombopag yagunyazwa yi-FDA yase-US ngo-2008 yokwelapha i-idiopathic thrombocytopenic purpura (ITP), nango-2014 ukuze kwelashwe i-aplastic anemia enzima (AA).Futhi isidakamizwa sokuqala esigunyazwe yi-US FDA sokwelapha i-AA eminyakeni engama-30 yakamuva.
Ngo-December 2012, i-US FDA yagunyaza i-Elthrombopag yokwelapha i-thrombocytopenia ezigulini ezine-hepatitis C (CHC) engapheli, ukuze iziguli ze-hepatitis C ezinokubikezelwa okungekuhle ngenxa yokubala kweplatelet ephansi zikwazi ukuqala futhi zilondoloze ukwelashwa okujwayelekile okusekelwe kwe-interferon kwezifo zesibindi.NgoFebhuwari3, 2014, i-GlaxoSmithKline yamemezela ukuthi i-FDA inikeze ukuphumelela komuthi wokwelapha i-Eltrombopag wokwelapha i-hemopenia ezigulini ezine-chemicalbook aplastic anemia (SAA) enzima kakhulu engazange iphendule ngokugcwele ku-immunotherapy.Ngomhla zingama-24 ku-Agasti, i-2015, i-US FDA igunyaze i-Eltrombopag yokwelashwa kwe-thrombocytopenia kubantu abadala kanye nezingane ezineminyaka engu-1 nangaphezulu ezine-immune immune thrombocytopenia (ITP) ezingenampendulo eyanele ku-corticosteroids, i-immunoglobulins noma i-splenectomy.NgoJanuwari4, 2018, i-Eltrombopag yagunyazwa ukuthi ifakwe ohlwini e-China ukuze zelashwe i-immune immune thrombocytopenia (ITP).
I-Quality First, kanye ne-Client Supreme iyisiqondiso sethu sokuletha usizo olungcono kakhulu kubathengi bethu. Kulezi zinsuku, besizama konke okusemandleni ethu ukuba phakathi kwabathumeli bangaphandle abafanelekile ngaphakathi kwenkundla yethu ukuze sanelise abathengi okwengeziwe abazodinga isitayela sase-Europe 3′- IHydroxy-3-Biphenylcarboxylic Acid Citric Acid 77-92-9, Ngaphezu kweminyaka engu-8 yebhizinisi elincane, manje sesiqongelele ulwazi olucebile nobuchwepheshe obuthuthukile phakathi nokukhiqizwa kwemikhiqizo yethu.
Isitayela saseYurophu seI-China 77-92-9 kanye ne-CAS 77-92-9, Ngokusekelwe emugqeni wethu wokukhiqiza ozenzakalelayo, isiteshi sokuthenga izinto ezizinzile kanye nezinhlelo ezisheshayo zenkontileka engaphansi kwakhiwe ezweni laseChina ukuze kuhlangatshezwane nemfuneko ebanzi nephakeme yamakhasimende eminyakeni yamuva.Besilokhu sibheke ngabomvu ukubambisana namakhasimende engeziwe emhlabeni wonke ukuze sithuthuke ngokufanayo futhi sizuze ngokufanayo!Ukwethemba kwakho nokugunyazwa kwakho kuwumvuzo ongcono kakhulu wemizamo yethu.Ngokuhlala sithembekile, sisungula izinto ezintsha futhi sisebenza kahle, silindele ngobuqotho ukuthi singaba ozakwethu bebhizinisi ukuze sakhe ikusasa lethu eliqhakazile!