Ikhwalithi enhle 99% 2-Cyanobenzyl Bromide;I-Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9

Ngeke nje sizame konke okusemandleni ethu ukunikeza izinkampani ezinhle kakhulu cishe kubo bonke abathengi, kodwa futhi sikulungele ukuthola noma isiphi isiphakamiso esinikezwa abathengi bethu ngekhwalithi Enhle engu-99% 2-Cyanobenzyl Bromide;I-Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Ithimba lefemu yethu kanye nokusetshenziswa kobuchwepheshe besimanje liletha okuthengiswayo kwekhwalithi enhle okuthandwa kakhulu futhi kwaziswa ngamathemba ethu emhlabeni jikelele.
Ngeke nje sizame konke okusemandleni ethu ukunikeza izinkampani ezinhle kakhulu cishe kubo bonke abathengi, kodwa futhi sikulungele ukuthola noma isiphi isiphakamiso esinikezwa abathengi bethuI-China 2-Cyanobenzyl Bromide Powder ne-Alpha-Bromo-O-Toluonitrile, Sikholelwa ngokuqinile ukuthi ubuchwepheshe kanye nensizakalo kuyisisekelo sethu namuhla futhi ikhwalithi izodala izindonga zethu ezithembekile zekusasa.Yithi kuphela esinekhwalithi engcono nengcono, singakwazi ukufeza amakhasimende ethu kanye nathi ngokwethu.Yamukela amakhasimende emhlabeni wonke ukuze uxhumane nathi ukuze uthole olunye ibhizinisi nobudlelwano obuthembekile.Besilokhu silapha sisebenzela izimfuno zakho noma nini lapho uzodinga.

Sebenzisa:Isiphakathi se-Linagliptin.

Sebenzisa:Isiphakathi se-Linagliptin
Izinga eliphezulu:izinga lebhizinisi
Isivivinyo:98-102%

Ingaphandle:Impushana emhlophe ukuya kokuphuzi
Iphakheji:25kg/isigubhu

Ukuhlaziya i-linagliptin ekhona nokhiye wayo omaphakathi 8-bromo-7-(2-butynyl)-3,7-dihydro-3-methyl-1--[(4-methyl -2-quinazolinyl)methyl)-1H-purine- 2,6-dione (11) indlela yokuhlanganisa, thola umzila wokwenziwa ofanele ukukhiqizwa kwezimboni.Indlela: fingqa izindlela ezihlukene zokwenziwa.Imiphumela neziphetho: Umzila 2.2 unenqubo elula uma kuqhathaniswa nezindleko eziphansi, ofaneleka kakhulu ukukhiqizwa kwezimboni.

I-8-bromo-3,7-dihydro-3-methyl-1H-purine-2,6-dione iyisihluthulelo esimaphakathi ekuhlanganisweni komuthi we-hypoglycemic linagliptin.I-synthesis ye-1 isebenzisa i-methyl urea ne-cyanoacetic acid njengezinto zokuqala, futhi ibhekana nezinyathelo eziyisithupha zokusabela kwe-condensation, i-cyclization, i-nitrosation, ukunciphisa, i-cyclization, ne-bromine enesivuno esiphelele esingu-46.3%.Izakhiwo zabo bonke abaphakathi ziqinisekiswe yi-1HNMR.

Ukusungulwa kwamanje kuhlobene nendlela elula yokulungiselela i-high-purity linagliptin.I-Quinazoline, isihluthulelo esimaphakathi sokulungiswa kwebhodwe elilodwa le-linagliptin 8 bromo 7 (2 butyne 1 base) 3,7 dihydro 3 methyl 1 [(4 methyl 2 quinazolinyl) methyl] 1H Purine 2,6 dione, okuphakathi kuhlukaniswe filtration, bese isabela nge-(R)3 aminopiperidine dihydrochloride ukuthola isixazululo esiqukethe i-linagliptin.Ngemuva kokuthi ikhambi eliqukethe i-linagliptin selicutshungulwe futhi, umkhiqizo ohlanzekile weDeliraliptin.Ukulungiswa kwesihluthulelo esiphakathi kokusungulwa kwamanje kusebenzisa indlela yebhodwe elilodwa, elilula ukusebenza futhi lithuthukise isivuno.Ngemuva kokuhlukaniswa kokhiye ophakathi nendawo, kusabela nge-(R)3 aminopiperidine dihydrochloride, ngaleyo ndlela Ukuthola i-linagliptin ehlanzekile futhi ihlangabezana nezidingo zokukhiqiza nezimemezelo zezinkampani zemithi ngezinga elikhulu kakhulu.

Ngeke nje sizame konke okusemandleni ethu ukunikeza izinkampani ezinhle kakhulu cishe kubo bonke abathengi, kodwa futhi sikulungele ukuthola noma isiphi isiphakamiso esinikezwa abathengi bethu ngekhwalithi Enhle engu-99% 2-Cyanobenzyl Bromide;I-Alpha-Bromo-O-Toluonitrile CAS: 22115-41-9, Ithimba lefemu yethu kanye nokusetshenziswa kobuchwepheshe besimanje liletha okuthengiswayo kwekhwalithi enhle okuthandwa kakhulu futhi kwaziswa ngamathemba ethu emhlabeni jikelele.
Ikhwalithi enhleI-China 2-Cyanobenzyl Bromide Powder ne-Alpha-Bromo-O-Toluonitrile, Sikholelwa ngokuqinile ukuthi ubuchwepheshe kanye nensizakalo kuyisisekelo sethu namuhla futhi ikhwalithi izodala izindonga zethu ezithembekile zekusasa.Yithi kuphela esinekhwalithi engcono nengcono, singakwazi ukufeza amakhasimende ethu kanye nathi ngokwethu.Yamukela amakhasimende emhlabeni wonke ukuze uxhumane nathi ukuze uthole olunye ibhizinisi nobudlelwano obuthembekile.Besilokhu silapha sisebenzela izimfuno zakho noma nini lapho uzodinga.