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Ikhwalithi ephezulu edayiswayo eshisayo CAS 78-96-6 99% Amino-2-Propanol / Isopropanolamine/ Monoisopropanolamine (MIPA)

Ikhwalithi ephezulu edayiswayo eshisayo CAS 78-96-6 99% Amino-2-Propanol / Isopropanolamine/ Monoisopropanolamine (MIPA)

Incazelo emfushane:

I-CAS no:376592-93-7

Izakhiwo zamakhemikhali:I-Elthrombopag Intermediates


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Sihlala sikholelwa ukuthi umlingiswa womuntu unquma izinga eliphezulu lemikhiqizo, imininingwane inquma izinga eliphezulu lemikhiqizo, kanye nomoya wabasebenzi OBUYIQINISO, OSEBENZA KANYE OKUSHA OKUSHA wekhwalithi ephezulu edayiswa ngokushisa i-CAS 78-96-6 99% Amino-2-Propanol / I-Isopropanolamine/ I-Monoisopropanolamine (MIPA), Sizokwenza imizamo eyengeziwe yokusiza abathengi basekhaya nabamazwe ngamazwe, futhi sikhiqize izinzuzo ezifanayo kanye nokubambisana okuphumelelayo phakathi kwethu.sikulindele ngokulangazela ukubambisana kwenu ngobuqotho.
Sikholelwa njalo ukuthi umlingiswa womuntu unquma izinga eliphezulu lemikhiqizo, imininingwane inquma izinga eliphezulu lemikhiqizo, kanye nomoya wabasebenzi OBUYIQINISO, OSEBENZA KANYE NOBUSHAI-China Mipa ne-Monoisopropanolamine, Sihlanganisa ukuklama, ukukhiqiza nokuthekelisa kanye nabasebenzi abanekhono abangaphezu kwe-100, uhlelo oluqinile lokulawula izinga kanye nobuchwepheshe abanolwazi. Sigcina ubudlelwano bebhizinisi besikhathi eside nabadayisi nabasabalalisi bakha amazwe angaphezu kuka-50, njenge-USA, UK, Canada, Europe kanye Afrika njll.

I-3′-Amino-2′-hydroxy-[1,1'-bipheny]-3-carboxylic acid isetshenziswa njengendawo emaphakathi ye-Eltrombopag.
I-Eltrombopag, eyakhiwe yi-GlaxoSmithKline (GSK) e-UK futhi kamuva yathuthukiswa ngokuhlanganyela ne-Novartis e-Switzerland, ingeyokuqala futhi iwukuphela kwe-molecule encane egunyazwe i-non-peptide TPO receptor agonist emhlabeni.I-Eltrombopag yagunyazwa yi-FDA yase-US ngo-2008 yokwelapha i-idiopathic thrombocytopenic purpura (ITP), nango-2014 ukuze kwelashwe i-aplastic anemia enzima (AA).Futhi isidakamizwa sokuqala esigunyazwe yi-US FDA sokwelapha i-AA eminyakeni engama-30 yakamuva.
Ngo-December 2012, i-US FDA yagunyaza i-Elthrombopag yokwelapha i-thrombocytopenia ezigulini ezine-hepatitis C (CHC) engapheli, ukuze iziguli ze-hepatitis C ezinokubikezelwa okungekuhle ngenxa yokubala kweplatelet ephansi zikwazi ukuqala futhi zilondoloze ukwelashwa okujwayelekile okusekelwe kwe-interferon kwezifo zesibindi.NgoFebhuwari3, 2014, i-GlaxoSmithKline yamemezela ukuthi i-FDA inikeze ukuphumelela komuthi wokwelapha i-Eltrombopag wokwelapha i-hemopenia ezigulini ezine-chemicalbook aplastic anemia (SAA) enzima kakhulu engazange iphendule ngokugcwele ku-immunotherapy.Ngomhla zingama-24 ku-Agasti, i-2015, i-US FDA igunyaze i-Eltrombopag yokwelashwa kwe-thrombocytopenia kubantu abadala kanye nezingane ezineminyaka engu-1 nangaphezulu ezine-immune immune thrombocytopenia (ITP) ezingenampendulo eyanele ku-corticosteroids, i-immunoglobulins noma i-splenectomy.NgoJanuwari4, 2018, i-Eltrombopag yagunyazwa ukuthi ifakwe ohlwini e-China ukuze zelashwe i-immune immune thrombocytopenia (ITP).

Sihlala sikholelwa ukuthi umlingiswa womuntu unquma izinga eliphezulu lemikhiqizo, imininingwane inquma izinga eliphezulu lemikhiqizo, kanye nomoya wabasebenzi OBUYIQINISO, OSEBENZA KANYE OKUSHA OKUSHA wekhwalithi ephezulu edayiswa ngokushisa i-CAS 78-96-6 99% Amino-2-Propanol / I-Isopropanolamine/ I-Monoisopropanolamine (MIPA), Sizokwenza imizamo eyengeziwe yokusiza abathengi basekhaya nabamazwe ngamazwe, futhi sikhiqize izinzuzo ezifanayo kanye nokubambisana okuphumelelayo phakathi kwethu.sikulindele ngokulangazela ukubambisana kwenu ngobuqotho.
Ukudayiswa okushisayoI-China Mipa ne-Monoisopropanolamine, Sihlanganisa ukuklama, ukukhiqiza nokuthekelisa kanye nabasebenzi abanekhono abangaphezu kwe-100, uhlelo oluqinile lokulawula izinga kanye nobuchwepheshe abanolwazi. Sigcina ubudlelwano bebhizinisi besikhathi eside nabadayisi nabasabalalisi bakha amazwe angaphezu kuka-50, njenge-USA, UK, Canada, Europe kanye Afrika njll.


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