Isaphulelo Esijwayelekile Esimaphakathi CAS.288573-56-8 1- (tert-Butoxycarbonyl) -4-[ (4-fluorophenyl) Amino]Piperidine

Sithembela ekucabangeni kwamasu, ukuthuthukiswa okuqhubekayo kuzo zonke izingxenye, intuthuko yezobuchwepheshe kanye nakubasebenzi bethu ababamba iqhaza ngokuqondile empumelelweni yethu ye-CAS Yesaphulelo Esijwayelekile Esimaphakathi.288573-56-8 1- (tert-Butoxycarbonyl) -4-[ (4-fluorophenyl) Amino]Piperidine, Izinto ziwine izitifiketi ngenkathi kusetshenziswa iziphathimandla eziyinhloko zesifunda nezamazwe ngamazwe.Ukuze uthole imininingwane eyengeziwe, sicela usithinte!
Sithembele ekucabangeni kwamasu, ukwenza ngcono okuqhubekayo kuzo zonke izingxenye, intuthuko yezobuchwepheshe kanye nakubasebenzi bethu ababamba iqhaza ngokuqondile empumelelweni yethuI-China [(4-fluorophenyl)amino] ne-fluorophenyl) Amino]Piperidine, Sisenkonzweni eqhubekayo kumakhasimende ethu akhulayo endawo nawamazwe ngamazwe.Sihlose ukuba umholi emhlabeni wonke kule mboni futhi ngalo mqondo;kuyinjabulo yethu enkulu ukusebenzela nokuletha amazinga aphezulu okwaneliseka phakathi kwezimakethe ezikhulayo.

I-2-bromo-2- (2-fluorophenyl) -1-cyclopropylethanone isetshenziswa njengendawo ephakathi ye-Prasugrel.
I-Prasugrel iyi-antiplatelet ye-thiophenopyridine eyakhiwe ngu-Eli Lilly kanye no-daiichisankyo, umkhiqizi wemithi waseJapane.Kuyisidakamizwa esandulelayo.Yakha i-molecule esebenzayo ngemva kwe-metabolism nge-cytochrome P450 esibindini futhi ihlangana ne-platelet P2Y12 receptor ukuze isebenze ngokumelene nokuhlanganiswa kweplatelet.Ucwaningo lwezokwelapha luye lwafakazela ukuthi umthamo we-60 mg unomphumela ongcono we-anticoagulant kuno-300 mg ojwayelekile kanye no-600 mg okhushulwe umthamo we-clopidogrel, onganciphisa ubungozi obuphelele bokuhlaselwa yinhliziyo, unhlangothi nokufa ngenxa yesifo senhliziyo ngama-20%, futhi kube nomphumela osheshayo. , umphumela omuhle wokwelapha, ukumelana nezidakamizwa okuhle kanye nokuba khona kwe-bioavailability, kanye nobuthi obuphansi.

Sithembela ekucabangeni kwamasu, ukuthuthukiswa okuqhubekayo kuzo zonke izingxenye, intuthuko yezobuchwepheshe kanye nakubasebenzi bethu ababamba iqhaza ngokuqondile empumelelweni yethu ye-CAS Yesaphulelo Esijwayelekile Esimaphakathi.288573-56-8 1- (tert-Butoxycarbonyl) -4-[ (4-fluorophenyl) Amino]Piperidine, Izinto ziwine izitifiketi ngenkathi kusetshenziswa iziphathimandla eziyinhloko zesifunda nezamazwe ngamazwe.Ukuze uthole imininingwane eyengeziwe, sicela usithinte!
Isaphulelo EsijwayelekileI-China [(4-fluorophenyl)amino] ne-fluorophenyl) Amino]Piperidine, Sisenkonzweni eqhubekayo kumakhasimende ethu akhulayo endawo nawamazwe ngamazwe.Sihlose ukuba umholi emhlabeni wonke kule mboni futhi ngalo mqondo;kuyinjabulo yethu enkulu ukusebenzela nokuletha amazinga aphezulu okwaneliseka phakathi kwezimakethe ezikhulayo.