Sithembela ekucabangeni kwamasu, ukwenza izinto zibe zesimanjemanje kuzo zonke izingxenye, intuthuko yezobuchwepheshe kanye nakubasebenzi bethu ababamba iqhaza ngokuqondile empumelelweni yethu Yomhlinzeki Othembekile wase-China L-Valine ukuze uthole Isengezo Sezempilo Se-Amino Acid Valine, Kusukela kwasungulwa uphiko lwezokukhiqiza, manje sizibophezele. ekuqhubekeleni phambili kwezimpahla ezintsha.Ngokuhambisana nesivinini senhlalo nezomnotho, sizoqhubeka nokuqhubekisela phambili umoya “wokuseqophelweni eliphezulu, ukusebenza kahle, ukusungula izinto ezintsha, ubuqotho”, futhi sihlale nomgomo wokusebenza “wesikweletu ekuqaleni, ikhasimende lokuqala, izinga elihle elihle kakhulu”.Sizokhiqiza ikusasa elihle kakhulu elibonakalayo ekuphumeni kwezinwele nabangane bethu.
Sithembele ekucabangeni kwamasu, ukwenza ngcono okuqhubekayo kuzo zonke izingxenye, intuthuko yezobuchwepheshe kanye nakubasebenzi bethu ababamba iqhaza ngokuqondile empumelelweni yethuI-China Valine, L Valine, Izinto zethu zithunyelwa emhlabeni wonke.Amakhasimende ethu ahlala enelisekile ngekhwalithi yethu ethembekile, izinsizakalo ezigxile kumakhasimende kanye namanani ancintisanayo.Umgomo wethu “ukuqhubeka nokuzuza ukwethembeka kwakho ngokunikela imizamo yethu ekwenzeni ngcono njalo izinto namasevisi ethu ukuze siqinisekise ukwaneliseka kwabasebenzisi bethu bokugcina, amakhasimende, abasebenzi, abahlinzeki kanye nemiphakathi yomhlaba wonke esibambisene kuyo”.
I-L-Valine isetshenziswa njenge-Intermediate ye-Valaciclovir.
I-Valacyclovir iyisidakamizwa se-analogue ye-guanine.Isetshenziselwa ukwelashwa kwe-herpes simplex kanye nokutheleleka kwe-herpes zoster ezifweni ezithathelwana ngocansi.Lo mkhiqizo uyisandulela se-acyclovir.Imuncwa ngokushesha ngemva kokuphathwa ngomlomo futhi iguqule ngokushesha ibe i-acyclovir emzimbeni.Umphumela wayo we-antiviral udlalwa yi-acyclovir.Ngemuva kokuthi i-acyclovir ingene kumaseli angenwe yi-herpes, iqhudelana ne-deoxynucleoside yegciwane i-thymidine deoxynucleoside kinase noma i-cell kinase, futhi umuthi ufakwa i-phosphorylated ku-activated acyclic guanosine triphosphate.Njengengxenye engaphansi yokuphindaphinda kwegciwane, i-acyclovir incintisana ne-deoxyguanine triphosphate ye-virus DNA polymerase, evimbela ukuhlanganiswa kwe-DNA yegciwane futhi ibonise umphumela wokunqanda amagciwane.Umsebenzi we-antiviral walo mkhiqizo ku-vivo ungcono kune-acyclovir, futhi inkomba yokwelapha ye-herpes simplex virus uhlobo I nohlobo lwe-II ingu-42.91% no-30.13% ngaphezu kwe-acyclovir ngokulandelanayo.Futhi inomphumela ophezulu wokwelapha ku-varicella zoster virus.
Sithembela ekucabangeni kwamasu, ukwenza izinto zibe zesimanjemanje kuzo zonke izingxenye, intuthuko yezobuchwepheshe kanye nakubasebenzi bethu ababamba iqhaza ngokuqondile empumelelweni yethu Yomhlinzeki Othembekile wase-China L-Valine ukuze uthole Isengezo Sezempilo Se-Amino Acid Valine, Kusukela kwasungulwa uphiko lwezokukhiqiza, manje sizibophezele. ekuqhubekeleni phambili kwezimpahla ezintsha.Ngokuhambisana nesivinini senhlalo nezomnotho, sizoqhubeka nokuqhubekisela phambili umoya “wokuseqophelweni eliphezulu, ukusebenza kahle, ukusungula izinto ezintsha, ubuqotho”, futhi sihlale nomgomo wokusebenza “wesikweletu ekuqaleni, ikhasimende lokuqala, izinga elihle elihle kakhulu”.Sizokhiqiza ikusasa elihle kakhulu elibonakalayo ekuphumeni kwezinwele nabangane bethu.
Umhlinzeki onokwethenjelwaI-China Valine, L Valine, Izinto zethu zithunyelwa emhlabeni wonke.Amakhasimende ethu ahlala enelisekile ngekhwalithi yethu ethembekile, izinsizakalo ezigxile kumakhasimende kanye namanani ancintisanayo.Umgomo wethu “ukuqhubeka nokuzuza ukwethembeka kwakho ngokunikela imizamo yethu ekwenzeni ngcono njalo izinto namasevisi ethu ukuze siqinisekise ukwaneliseka kwabasebenzisi bethu bokugcina, amakhasimende, abasebenzi, abahlinzeki kanye nemiphakathi yomhlaba wonke esibambisene kuyo”.