Rivaroxaban(S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Rivaroxaban(S)-Rivaroxaban;BAY 59-7939;RivaroxabanIsomer;Rivaroxaban;
Isetshenziswa ezigulini ezikhulile ezinokuhlinzwa okukhethiwe kwe-hip noma idolo ukuvimbela i-venous thrombosis (VTE).
Isetshenziselwa ukuvimbela noma ukunciphisa ukwakheka kwe-thrombosis, i-deep vein thrombosis (DVT) kanye ne-pulmonary embolism (PE) ngemva kokuhlinzwa esikhundleni se-hip noma amadolo.
Umthamo onconyiwe yi-rivaroxaban yomlomo 10mg, kanye ngosuku.I-Rivaroxaban 10mg ingathathwa ngokudla noma yodwa.I-Rivaroxaban 15mg noma amaphilisi angu-20mg kufanele athathwe nokudla.
standard: usp40
Isilinganiso: 99-102%
Ingaphandle: Impushana emhlophe
Iphakheji: 25kg / isigubhu
Thatha 4-(4-aminophenyl) morpholin-3-one (SM-1), (S)-N-glycidyl phthalimide (SM-2), 5-chlorothiophene-2- Formyl chloride (SM-3) into yokuqala .Ngemuva kwe-condensation, i-cyclization, i-aminolysis kanye ne-acylation, i-rivaroxaban engahluziwe iyatholakala, futhi i-rivaroxaban eqediwe iyacwengwa.
Ukulungiselela: Lo mkhiqizo uyithebhulethi ebomvu ehlanganiswe nefilimu.
Izinsiza:
Umgogodla wethebhulethi: i-microcrystalline cellulose, i-croscarmellose sodium, i-lactose monohydrate, i-hypromellose, i-sodium lauryl sulfate, i-magnesium stearate
Ukugqoka: i-polyethylene glycol, i-hypromellose, i-titanium dioxide, i-iron oxide ebomvu
I-Rivaroxaban iyisidakamizwa esikhethwa kakhulu, esithathwa ngomlomo esivimbela ngokuqondile i-factor Xa.Ngokuvinjelwa okukhetha kakhulu nokuncintisana kwe-factor Xa yamahhala nebophekile kanye nomsebenzi we-prothrombin, andisa ipuleti lesikhathi le-thromboplastin elicushiwe (PT) kanye nesikhathi se-prothrombin (aPTT) ngendlela encike kumthamo, engaphazamisa impophoma yokuhlangana. kuvimbela ukukhiqizwa kwe-thrombin ne-thrombosis.I-Rivaroxaban ayivimbeli i-thrombin (isici esisebenzayo Ⅱ), futhi ayizange ifakazele ukuthi inomthelela kumaplatelet.
Umehluko obalulekile phakathi kwe-rivaroxaban ne-fondaparinux/heparin ukuthi ayidingi ukubamba iqhaza kwe-antithrombin III futhi ingaphikisa ngokuqondile i-factor Xa yamahhala neboshiwe;kuyilapho i-heparin idinga i-antithrombin III ukuze isebenze, futhi Ayinawo umphumela ku-factor Xa ku-prothrombin complex.
I-JIN DUN Medical ineIziqu ze-ISO futhi ihlangabezana namazinga okukhiqiza e-GMP, kuqashwe ochwepheshe basekhaya nabangaphandle abanolwazi olunzulu lokuqondisa i-R&D yenkampani.
TECHNOL OGY UBUHLE
●I-High Pressure Catalytic Hydrogenation.I-High Pressure Hydrogenolysis Reaction .Ukusabela kwe-Cryogenic (<-78%C)
● I-Aromatic Heterocyclic Synthesis
●Ukusabela Kabusha
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Ukusabela kukaGiignard
Izisetshenziswa
Ilebhu yethu inezinsiza ezihlukahlukene zokuhlola nokuhlola, njenge: NMR (Bruker 400M), HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, i-Differential Scanning Calorimeter (DSC), i-Electron Microscope...
Ithimba le-R&D
I-Jindun Medical ineqembu labasebenzi abangochwepheshe be-R&D, futhi isebenzisa ochwepheshe abaningi bokwenziwa kwezidakamizwa basekhaya nabangaphandle ukuze baqondise i-R&D, okwenza ukuhlanganiswa kwethu kunembe kakhudlwana futhi kusebenze kahle.
Sisize izinkampani ezimbalwa eziphezulu zasekhaya ezithaka imithi, njengeI-Hansoh, i-Hengrui ne-HEC Pharm.Lapha sizokhombisa ingxenye yazo.
Ikesi Lokwenza Ngokwezifiso:
Inombolo yeCas: 110351-94-5
Ikesi Lokwenza Ngokwezifiso:
Inombolo yeCas: 144848-24-8
Ikesi Lesithathu Lokwenza Ngokwezifiso:
Inombolo yeCas: 200636-54-0
1.Enza ngendlela oyifisayo i-New Intermediates noma ama-API.Ngokufanayo nokwabelana kwecala elingenhla, amakhasimende anezidingo ze-Intermediates ethile noma ama-API, futhi awakwazi ukuthola imikhiqizo edingekayo emakethe, lapho-ke singasiza Ukwenza Ngokwezifiso.
2.Ukuthuthukisa Inqubo Yemikhiqizo Emidala.Ithimba lethu lizosiza Ukuthuthukisa futhi lithuthukise ukukhiqiza okunjalo okuyindlela yokusabela endala, izindleko zokukhiqiza ziphezulu, nokusebenza kahle kuphansi.Singahlinzeka ngemibhalo egcwele yokudluliswa kobuchwepheshe kanye nokuthuthukiswa kwenqubo, sisize ikhasimende ngokukhiqiza okuphumelelayo.
Ukusuka kokuhlosiwe kwezidakamizwa kuye kuma-IND, i-JIN DUN Medical ikunikezaizixazululo zomuntu siqu ze-R&D zokuma okukodwa.
I-JIN DUN Medical iphikelela ekwakheni iqembu elinamaphupho, ukwenza imikhiqizo enesizotha, ecophelelayo, eqinile, futhi siphume konke ukuze sibe uzakwethu othembekile nomngane wamakhasimende!
![I-Casp ungin Acetate;Caspofungin acetate;Cancidas;Caspofungin acetate [USAN:BAN:JAN];](http://cdn.globalso.com/jindunchem-med/fbe17385-300x300.jpg)