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Intengo Ekhethekile Yempahla Engavuthiwe Yemithi Ephakathi Nezilwa Namagciwane I-Guanine CAS#73-40-5

Intengo Ekhethekile Yempahla Engavuthiwe Yemithi Ephakathi Nezilwa Namagciwane I-Guanine CAS#73-40-5

Incazelo emfushane:

I-CAS no: 118-00-3

Izakhiwo zamakhemikhali: I-Valaciclovir Intermediates


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Ukuqamba izinto ezintsha, okuhle kakhulu kanye nokwethembeka yikona okuwumongo wenhlangano yethu.Lezi zimiso namuhla ngaphezu kwanini ngaphambili zakha isisekelo sempumelelo yethu njengenhlangano yamazwe omhlaba ephakathi nendawo Yenani Elikhethekile Lempahla Ephakathi Yokulwa Ngamagciwane I-Guanine CAS#73-40-5, Sibheke phambili ekusunguleni ibhizinisi lesikhathi eside. izinhlangano nabathengi bomhlaba.
Ukuqamba izinto ezintsha, okuhle kakhulu kanye nokwethembeka yikona okuwumongo wenhlangano yethu.Le migomo namuhla eyengeziwe kunangaphambili yakha isisekelo sempumelelo yethu njengenhlangano esebenza emhlabeni wonke yosayizi ophakathi nendawoI-China Phramaceutical Chemical and API, Ukuvumela amakhasimende abe nokuzethemba okwengeziwe kithi futhi athole isevisi enethezekile, siqhuba inkampani yethu ngokwethembeka, ubuqotho kanye nekhwalithi engcono kakhulu.Sikholelwa ngokuqinile ukuthi kuyinjabulo yethu ukusiza amakhasimende ukuthi aqhube ibhizinisi lawo ngempumelelo kakhudlwana, nokuthi izeluleko zethu ezinokuhlangenwe nakho kanye nesevisi kungaholela ekukhetheni okufanele kakhudlwana kumakhasimende.

I-Guanosine isetshenziswa njenge-Intermediate ye-Valaciclovir.
I-Valacyclovir iyisidakamizwa se-analogue ye-guanine.Isetshenziselwa ukwelashwa kwe-herpes simplex kanye nokutheleleka kwe-herpes zoster ezifweni ezithathelwana ngocansi.Lo mkhiqizo uyisandulela se-acyclovir.Imuncwa ngokushesha ngemva kokuphathwa ngomlomo futhi iguqule ngokushesha ibe i-acyclovir emzimbeni.Umphumela wayo we-antiviral udlalwa yi-acyclovir.Ngemuva kokuthi i-acyclovir ingene kumaseli angenwe yi-herpes, iqhudelana ne-deoxynucleoside yegciwane i-thymidine deoxynucleoside kinase noma i-cell kinase, futhi umuthi ufakwa i-phosphorylated ku-activated acyclic guanosine triphosphate.Njengengxenye engaphansi yokuphindaphinda kwegciwane, i-acyclovir incintisana ne-deoxyguanine triphosphate ye-virus DNA polymerase, evimbela ukuhlanganiswa kwe-DNA yegciwane futhi ibonise umphumela wokunqanda amagciwane.Umsebenzi we-antiviral walo mkhiqizo ku-vivo ungcono kune-acyclovir, futhi inkomba yokwelapha ye-herpes simplex virus uhlobo I nohlobo lwe-II ingu-42.91% no-30.13% ngaphezu kwe-acyclovir ngokulandelanayo.Futhi inomphumela ophezulu wokwelapha ku-varicella zoster virus.

Ukuqamba izinto ezintsha, okuhle kakhulu kanye nokwethembeka yikona okuwumongo wenhlangano yethu.Lezi zimiso namuhla ngaphezu kwanini ngaphambili zakha isisekelo sempumelelo yethu njengenhlangano yamazwe omhlaba ephakathi nendawo Yenani Elikhethekile Lempahla Ephakathi Yokulwa Ngamagciwane I-Guanine CAS#73-40-5, Sibheke phambili ekusunguleni ibhizinisi lesikhathi eside. izinhlangano nabathengi bomhlaba.
Intengo Ekhethekile yeI-China Phramaceutical Chemical and API, Ukuvumela amakhasimende abe nokuzethemba okwengeziwe kithi futhi athole isevisi enethezekile, siqhuba inkampani yethu ngokwethembeka, ubuqotho kanye nekhwalithi engcono kakhulu.Sikholelwa ngokuqinile ukuthi kuyinjabulo yethu ukusiza amakhasimende ukuthi aqhube ibhizinisi lawo ngempumelelo kakhudlwana, nokuthi izeluleko zethu ezinokuhlangenwe nakho kanye nesevisi kungaholela ekukhetheni okufanele kakhudlwana kumakhasimende.


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