2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile

I-2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile isetshenziswa njengendawo emaphakathi ye-Trelagliptin succinate.

I-Trogliptin succinate iyi-dipeptidyl peptidase Ⅳ (DPP - Ⅳ) inhibitor eyakhiwe yi-Takeda (Takeda Pharmaceutical Co., Ltd.) e-Japan.Ingavimbela i-DPP - Ⅳ ngokukhetha nangokuqhubekayo futhi ilawule izinga likashukela egazini.Izivivinyo zokwelashwa zibonisa ukuthi umuthi unokuphepha okuhle nokusebenza kahle.Kanye ngeviki kungalawula ngempumelelo izinga likashukela egazini futhi kuthuthukise ukuthobela imithi yeziguli.NgoMeyi, 2015, umuthi wagunyazwa yi-PMDA yaseJapan ukuthi ufakwe ohlwini lokwelapha isifo sikashukela.