I-Hydroxypyrazolodpyrimidine pyrazolo(3,4-d)pyrimidin-1-ol
I-Hydroxypyrazolodpyrimidine pyrazolo(3,4-d)pyrimidin-1-ol
Isetshenziswa emtholampilo ku-hyperuricemia eyinhloko neyesibili, ikakhulukazi ezigulini ezine-hyperuricemia, kanye nasezigulini ezinokwehluleka kwezinso, nasezigulini ezine-gout ephindaphindiwe noma engapheli, kanye nasezigulini ezine-Hyperuricemia.Isetshenziswa ezigulini ezine-Gouty nephropathy ukunciphisa izimpawu nokunciphisa ukwakheka kwamatshe e-uric acid ezinso;amatshe e-gout;esetshenziswa ku-uric acid ezinso zamatshe kanye nesifo sezinso se-uric acid.
Lo mkhiqizo kanye nama-metabolites awo angavimbela i-xanthine oxidase, ukuze i-hypoxanthine ne-xanthine ingaguqulelwa ku-uric acid, okungukuthi, ukwakheka kwe-uric acid kuncipha, ngaleyo ndlela kunciphise ukugcwala kwe-uric acid egazini futhi kunciphise ukugcwala kwe-urate egazini. amathambo, Amalunga nezinso, izidakamizwa ezingavimbela ukwakheka kwe-uric acid.Lo mkhiqizo ungavimbela umsebenzi wama-enzyme ezidakamizwa zesibindi.
(1) .I-hyperuricemia eyinhloko neyesibili, ikakhulukazi lezo ezinokukhiqizwa kwe-uric acid ngokweqile, nazo zisetshenziselwa i-hyperuricemia ngokuhluleka kwezinso;
(2) .Ukuze ukwelashwa kwe-gout, kufanelekile i-gout ephindaphindiwe noma engapheli.Ezigulini ezine-gouty nephropathy, ingakhulula izimpawu futhi inciphise ukwakheka kwamatshe e-uric acid ezinso;
(3) .i-Tophi;
(4) .Isetshenziselwa amatshe ezinso ze-uric acid kanye (noma) i-uric acid nephropathy.
Okujwayelekile:usp42
Isivivinyo:98-102%
Ingaphandle:Impushana emhlophe noma ecishe ibe mhlophe
Iphakheji :25kg/isikhwama
Kukhona ukucindezelwa komnkantsha, okungabangela i-pancytopenia, futhi umuthi kufanele uyekwe uma kunesidingo.Phuza amanzi amaningi ngesikhathi somuthi, futhi wenze umchamo ungathathi hlangothi noma ube ne-alkaline ukuze ukhiphe i-diuretic acid.Lo mkhiqizo kufanele usetshenziswe ngemuva kokunyamalala okukhulu kwe-gouty arthritis (imvamisa cishe amasonto amabili ngemuva kokuqala).Ngesikhathi somuthi, isithombe segazi nesibindi kanye nokusebenza kwezinso kufanele kuhlolwe njalo.
I-JIN DUN Medical ineIziqu ze-ISO futhi ihlangabezana namazinga okukhiqiza e-GMP, kuqashwe ochwepheshe basekhaya nabangaphandle abanolwazi olunzulu lokuqondisa i-R&D yenkampani.
TECHNOL OGY UBUHLE
●I-High Pressure Catalytic Hydrogenation.I-High Pressure Hydrogenolysis Reaction .Ukusabela kwe-Cryogenic (<-78%C)
● I-Aromatic Heterocyclic Synthesis
●Ukusabela Kabusha
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Ukusabela kukaGiignard
Izisetshenziswa
Ilebhu yethu inezinsiza ezihlukahlukene zokuhlola nokuhlola, njenge: NMR (Bruker 400M), HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, i-Differential Scanning Calorimeter (DSC), i-Electron Microscope...
Ithimba le-R&D
I-Jindun Medical ineqembu labasebenzi abangochwepheshe be-R&D, futhi isebenzisa ochwepheshe abaningi bokwenziwa kwezidakamizwa basekhaya nabangaphandle ukuze baqondise i-R&D, okwenza ukuhlanganiswa kwethu kunembe kakhudlwana futhi kusebenze kahle.
Sisize izinkampani ezimbalwa eziphezulu zasekhaya ezithaka imithi, njengeI-Hansoh, i-Hengrui ne-HEC Pharm.Lapha sizokhombisa ingxenye yazo.
Ikesi Lokwenza Ngokwezifiso:
Inombolo yeCas: 110351-94-5
Ikesi Lokwenza Ngokwezifiso:
Inombolo yeCas: 144848-24-8
Ikesi Lesithathu Lokwenza Ngokwezifiso:
Inombolo yeCas: 200636-54-0
1.Enza ngendlela oyifisayo i-New Intermediates noma ama-API.Ngokufanayo nokwabelana kwecala elingenhla, amakhasimende anezidingo ze-Intermediates ethile noma ama-API, futhi awakwazi ukuthola imikhiqizo edingekayo emakethe, lapho-ke singasiza Ukwenza Ngokwezifiso.
2.Ukuthuthukisa Inqubo Yemikhiqizo Emidala.Ithimba lethu lizosiza Ukuthuthukisa futhi lithuthukise ukukhiqiza okunjalo okuyindlela yokusabela endala, izindleko zokukhiqiza ziphezulu, nokusebenza kahle kuphansi.Singahlinzeka ngemibhalo egcwele yokudluliswa kobuchwepheshe kanye nokuthuthukiswa kwenqubo, sisize ikhasimende ngokukhiqiza okuphumelelayo.
Ukusuka kokuhlosiwe kwezidakamizwa kuye kuma-IND, i-JIN DUN Medical ikunikezaizixazululo zomuntu siqu ze-R&D zokuma okukodwa.
I-JIN DUN Medical iphikelela ekwakheni iqembu elinamaphupho, ukwenza imikhiqizo enesizotha, ecophelelayo, eqinile, futhi siphume konke ukuze sibe uzakwethu othembekile nomngane wamakhasimende!
![1,4′-Bipiperidine]-1′-carbonyl chloride HCl](http://cdn.globalso.com/jindunchem-med/image211-300x300.png)
