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( R )-2,3-o-isopropylidene-glyceraldehyde

( R )-2,3-o-isopropylidene-glyceraldehyde

Incazelo emfushane:

I-CAS no:15186-48-8

Izakhiwo zamakhemikhali: I-Gemcitabine Intermediates


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isebenzisa

(R) -2,3-o-isopropylidene-glyceraldehyde isetshenziswa njengendawo ephakathi yeGemcitabine.
I-Gemcitabine iyi-analogue ye-pyrimidine nucleotide, eyingxenye yezidakamizwa ezilwa nomdlavuza.Kungavimbela ukuqhubeka kwe-DNA synthesis esikhathini esithile, okungukuthi, isigaba S.Inezici ze-spectrum ebanzi ye-anticancer, indlela eyingqayizivele yokwenza, ubuthi obuphansi, akukho ukumelana okuphambene nezinye izidakamizwa ze-chemotherapeutic futhi akukho ubuthi obuphezulu.Namuhla, i-gemcitabine igunyazwe ukuthi isetshenziswe emazweni angaphezu kuka-90, isiba umuthi womugqa wokuqala wokwelapha umdlavuza wamaphaphu wengqamuzana ongewona omncane kanye “nezinga legolide” lokwelapha umdlavuza wamaphaphu.


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