I-2-cyano -5- fluorine benzyl bromide

2- cyano -5- fluorine benzyl bromide Isithombe Esifakiwe

I-2-cyano -5- fluorine benzyl bromide

Incazelo emfushane:

I-CAS no:421552-12-7

Izakhiwo zamakhemikhali: I-Trelagliptin succinate Intermediates

Thumela i-imeyili kithi

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isebenzisa

I-2-cyano -5- fluorine benzyl bromide isetshenziswa njengendawo emaphakathi ye-Trelagliptin succinate.
I-Trogliptin succinate iyi-dipeptidyl peptidase Ⅳ (DPP - Ⅳ) inhibitor eyakhiwe yi-Takeda (Takeda Pharmaceutical Co., Ltd.) e-Japan.Ingavimbela i-DPP - Ⅳ ngokukhetha nangokuqhubekayo futhi ilawule izinga likashukela egazini.Izivivinyo zokwelashwa zibonisa ukuthi umuthi unokuphepha okuhle nokusebenza kahle.Kanye ngeviki kungalawula ngempumelelo izinga likashukela egazini futhi kuthuthukise ukuthobela imithi yeziguli.NgoMeyi, 2015, umuthi wagunyazwa yi-PMDA yaseJapan ukuthi ufakwe ohlwini lokwelapha isifo sikashukela.

Okwedlule: L-Valine

Olandelayo: 2-((6-chloro-3-Methyl-2,4-dioxo-3,4-dihydropyriMidin-1(2H)-yl)Methyl)-4-fluorobenzonitrile

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