I-Ethyl bromo-difluroacetate

I-Ethyl bromo-difluroacetate isetshenziswa njengendawo ephakathi yeGemcitabine.
I-Gemcitabine iyi-analogue ye-pyrimidine nucleotide, eyingxenye yezidakamizwa ezilwa nomdlavuza.Kungavimbela ukuqhubeka kwe-DNA synthesis esikhathini esithile, okungukuthi, isigaba S.Inezici ze-spectrum ebanzi ye-anticancer, indlela yokusebenza eyingqayizivele, ubuthi obuphansi, akukho ukumelana nezinye izidakamizwa ze-chemotherapeutic futhi akukho ubuthi obuphezulu.Namuhla, i-gemcitabine igunyazwe ukuthi isetshenziswe emazweni angaphezu kuka-90, isiba umuthi womugqa wokuqala wokwelapha umdlavuza wamaphaphu wengqamuzana ongewona omncane kanye “nezinga legolide” lokwelapha umdlavuza wamaphaphu.