• NEBANNER

i-pentamethylene bis[1-(3,4-dimethoxybenzyl)-3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], i-dioxalate

i-pentamethylene bis[1-(3,4-dimethoxybenzyl)-3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], i-dioxalate

Incazelo emfushane:

I-CAS no:64228-78-0

Izakhiwo zamakhemikhali: I-Cisatracurium besylate Intermediates


Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isebenzisa

i-pentamethylene bis [1-(3,4-dimethoxybenzyl) -3,4-dihydro-6,7-dimethoxy-1H-isoquinoline-2-propionate], i-dioxalate isetshenziswa njengendawo ephakathi ye-Cisatracurium besylate.
I-Cisatracurium besylate uhlobo lukasawoti lwe-benzene sulfonate lwe-atracurium.Iwuhlobo lweziphumuli zokwenziwa zokwenziwa ezingezona-depolarizing ezinendima yazo efana ne-tubocurarine.Inesikhathi sokuqala seminithi elingu-1 kanye nesikhathi sobude bemizuzu eyi-15.Umthamo wokwelapha awuthinti inhliziyo, isibindi nokusebenza kwezinso.Futhi ayinayo impahla yokuqongelela.Kungase futhi kubangele ukukhululwa kwe-histamine uma isetshenziswa ngemithamo emikhulu.Ukuze uthole ukuphumula kwemisipha noma ukulawula ukuphefumula okudingekayo ekuhlinzeni, uma kuqhathaniswa nezidakamizwa zamanje zomtholampilo ezinkulu eziphumuza imisipha, i-cisatracurium besylate ayifakwanga i-metabolized ngesibindi noma izinso, futhi inokusimama kwenhliziyo;umphumela wawo wokuphumula kwemisipha unamandla izikhathi ezingu-3 njenge-atracurium ngaphandle kwemiphumela emibi yenhliziyo.I-Cisatracurium besylate isetshenziswa ngokuyinhloko ku-anesthesia ejwayelekile, futhi ingasetshenziswa kabanzi ekungeneni, ekwelapheni ukungasebenzi kahle kwesibindi nezinso, okusetshenziselwa ukuhlinzwa kwenhliziyo nemithambo yegazi kanye neziguli ezikhulile nezezingane.
Uma kuqhathaniswa ne-atracurium, lo mkhiqizo awunayo imiphumela emibi encike kumthamo wokukhishwa kwe-histamine;Nokho, okubi ukuthi iziguli ezinokukhubazeka kwesibindi nezinso kufanele zilawule ngokuqapha.
Kusukela ngo-1996 ngokokuqala ngqa lapho lesi sidakamizwa singena emakethe e-UK, amazwe angaphandle asebenzise kancane kancane ukuze athathe indawo ye-vecuronium ne-atracurium njengendlela evamile yokuphumula kwemisipha yomtholampilo.

Ulayini Womkhiqizo Ohlanganisiwe Wezinsiza

wps_doc_0

Isitifiketi

I-JIN DUN Medical ineIziqu ze-ISO futhi ihlangabezana namazinga okukhiqiza e-GMP, kuqashwe ochwepheshe basekhaya nabangaphandle abanolwazi olunzulu lokuqondisa i-R&D yenkampani.

13
d68590fe
12
111

Izinzuzo Zokwenza Ngokwezifiso Kwezokwelapha

TECHNOL OGY UBUHLE
●I-High Pressure Catalytic Hydrogenation.I-High Pressure Hydrogenolysis Reaction .Ukusabela kwe-Cryogenic (<-78%C)
● I-Aromatic Heterocyclic Synthesis
●Ukusabela Kabusha
●Chiral Resolution
●Heck, Suzuki,Negishi,Sonogashira .Ukusabela kukaGiignard

I-JIN DUN R&D

Izisetshenziswa

Ilebhu yethu inezinsiza ezihlukahlukene zokuhlola nokuhlola, njenge: NMR (Bruker 400M), HPLC、chiral-HPLC、LC-MS、LC-MS/MS (API 4000),IR,UV,GC,GC,GC-MS, Chromatography, I-Microwave Synthesizer, i-Parallel Synthesizer, i-Differential Scanning Calorimeter (DSC), i-Electron Microscope...

Ithimba le-R&D

I-Jindun Medical ineqembu labasebenzi abangochwepheshe be-R&D, futhi isebenzisa ochwepheshe abaningi bokwenziwa kwezidakamizwa basekhaya nabangaphandle ukuze baqondise i-R&D, okwenza ukuhlanganiswa kwethu kunembe kakhudlwana futhi kusebenze kahle.

wps_doc_3

Ukwabelana Kwamacala

Sisize izinkampani ezimbalwa eziphezulu zasekhaya ezithaka imithi, njengeI-Hansoh, i-Hengrui ne-HEC Pharm.Lapha sizokhombisa ingxenye yazo.

wps_doc_4

Ikesi Lokwenza Ngokwezifiso:

Inombolo yeCas: 110351-94-5

wps_doc_5

Ikesi Lokwenza Ngokwezifiso:

Inombolo yeCas: 144848-24-8

wps_doc_6

Ikesi Lesithathu Lokwenza Ngokwezifiso:

Inombolo yeCas: 200636-54-0

Imodi Yokubambisana

1.Enza ngendlela oyifisayo i-New Intermediates noma ama-API.Ngokufanayo nokwabelana kwecala elingenhla, amakhasimende anezidingo ze-Intermediates ethile noma ama-API, futhi awakwazi ukuthola imikhiqizo edingekayo emakethe, lapho-ke singasiza Ukwenza Ngokwezifiso.

2.Ukuthuthukisa Inqubo Yemikhiqizo Emidala.Ithimba lethu lizosiza Ukuthuthukisa futhi lithuthukise ukukhiqiza okunjalo okuyindlela yokusabela endala, izindleko zokukhiqiza ziphezulu, nokusebenza kahle kuphansi.Singahlinzeka ngemibhalo egcwele yokudluliswa kobuchwepheshe kanye nokuthuthukiswa kwenqubo, sisize ikhasimende ngokukhiqiza okuphumelelayo.

Ukusuka kokuhlosiwe kwezidakamizwa kuye kuma-IND, i-JIN DUN Medical ikunikezaizixazululo zomuntu siqu ze-R&D zokuma okukodwa.

I-JIN DUN Medical iphikelela ekwakheni iqembu elinamaphupho, ukwenza imikhiqizo enesizotha, ecophelelayo, eqinile, futhi siphume konke ukuze sibe uzakwethu othembekile nomngane wamakhasimende!


  • Okwedlule:
  • Olandelayo:

  • Bhala umyalezo wakho lapha futhi usithumelele wona